Red Sox vs. Pirates

BRADENTON -- The Red Sox are back at McKechnie Field for the second time in 10 days to face the Pirates. This time, though, they've left the heavy hitters at home with rookie outfielder Rusney Castillo as the biggest name in their lineup. 

Wade Miley is on the mound and Boston is using a designated hitter.

Red Sox lineup:

Rusney Castillo - CF

Daniel Nava - 1B

Allen Craig - LF

Garin Cecchini - DH

Jemile Weeks - 3B

Humberto Quintero - C

Jackie Bradley Jr. - RF

Deven Marrero - SS

Jeff Bianchi - 2B

Pittsburgh has Opening Day starter Francisco Liriano on the mound for the first time since he was formally announced as the starter for the opener by manager Clint Hurdle. Andrew McCutchen is out of the lineup for the eighth straight game as he continues to deal with "lower body soreness."

Pirates lineup:

Jose Tabata - RF

Neil Walker - 2B

Starling Marte - CF

Corey Hart - 1B

Francisco Cervelli - C

Sean Rodriguez - 3B

Gorkys Hernandez - LF

Gustavo Nunez - SS

Francisco Liriano - LHP

First pitch is at 1:05 p.m.